What Strategies Minimize Protein Degradation During Extended Expression?
Protein degradation is a major challenge in biotechnology and pharmaceutical production, potentially resulting in significant product loss and reduced yields. What strategies minimize protein degradation during extended expression? Key strategies include lowering expression temperature to 15-25°C, using protease-deficient host strains, and adding protease inhibitors to the culture medium. While these core strategies are effective, there’s…
Scientific Asia