Introduction
When it comes to non-surgical facial rejuvenation, Botox and Xeomin are two of the most popular choices. Both injectables help reduce wrinkles and fine lines, but they have key differences that impact their effectiveness, longevity, cost, and side effects. In this guide, we’ll compare Xeomin vs Botox in detail, covering everything from before and after results to cost, unit measurements, side effects, and which lasts longer.
What is Botox?
Botox is a neurotoxin derived from Clostridium botulinum that temporarily paralyzes facial muscles, reducing the appearance of dynamic wrinkles. It was the first FDA-approved neuromodulator and has been widely used for cosmetic and medical purposes.
Common Uses of Botox
- Forehead wrinkles
- Crow’s feet
- Frown lines (glabellar lines)
- Neck bands
- Excessive sweating (hyperhidrosis)
- Chronic migraines
What is Xeomin?
Xeomin, like Botox, is a botulinum toxin type A injectable used to reduce facial wrinkles. However, unlike Botox, it is free from complexing proteins, making it a “naked” neurotoxin. This purified formulation may reduce the risk of resistance, allowing it to work more effectively over time for some patients.
Common Uses of Xeomin
- Frown lines
- Crow’s feet
- Forehead wrinkles
- Cervical dystonia (neck muscle spasms)
- Blepharospasm (eyelid twitching)
Xeomin vs Botox: Key Differences
1. Composition and Purity
- Botox contains protective complexing proteins along with botulinum toxin A.
- Xeomin is a purified form of botulinum toxin A, meaning it lacks accessory proteins.
Key Takeaway: Patients who develop resistance to Botox due to repeated exposure to its proteins may respond better to Xeomin.
2. Before and After Results
Patients using Botox or Xeomin typically see results within 3-7 days, with full effects appearing after 14 days. Here’s a breakdown of results based on patient experiences:
| Feature | Botox | Xeomin |
| Onset Time | 3-5 days | 4-7 days |
| Peak Results | 14 days | 14 days |
| Duration | 3-4 months | 3-4 months |
| Natural Look | Yes | Yes |
| Resistance Risk | Higher (protein-based) | Lower (pure toxin) |
3. Unit Comparison: Xeomin vs Botox Units
Botox and Xeomin have a 1:1 unit conversion ratio. This means:
- If a patient needs 20 units of Botox, they will need 20 units of Xeomin for the same effect.
- However, individual metabolism and muscle strength may slightly alter dosage requirements.
4. Cost Comparison: Xeomin vs Botox Cost
- Botox: Typically costs between $10-$15 per unit
- Xeomin: Usually ranges from $8-$13 per unit
A single Botox or Xeomin treatment requires 20-50 units, leading to an average session cost of $200-$600.
Tip: Some clinics offer loyalty programs for Botox or Xeomin, which can reduce costs over time.
5. Which Lasts Longer?
Both Xeomin and Botox last about 3-4 months on average. However:
- Some studies suggest Xeomin may last slightly longer in patients who have built up resistance to Botox.
- Individual metabolism, lifestyle, and injection technique influence longevity.
6. Side Effects: Xeomin vs Botox Side Effects
Both injectables have similar mild side effects, including:
- Redness or swelling at the injection site
- Bruising
- Headaches
- Drooping eyelid (rare)
However, Botox’s complexing proteins may increase the risk of developing resistance over time.
Related Blogs:
Dysport vs Botox: Which is Right for You? Compare Benefits & Results
What is the difference between Botox and Dysport?
Hospitals, Clinics, and Experts Offering Botox & Xeomin
Here are some well-known medical spas, dermatologists, and plastic surgeons offering Botox and Xeomin treatments:
Top Clinics in the U.S.:
- Mayo Clinic – Offers both Botox and Xeomin for cosmetic and medical applications.
- Cleveland Clinic – Specializes in non-surgical aesthetic treatments.
- SkinSpirit Medical Spa (California) – Renowned for facial injectables.
- Dr. Michele Green, MD (NYC) – Board-certified dermatologist specializing in Botox and Xeomin.
- Eternal Dermatology (Maryland) – Known for advanced skin treatments.
Conclusion: Xeomin or Botox – Which One is Right for You?
Both Xeomin and Botox are excellent choices for reducing facial wrinkles. The decision depends on factors such as cost, purity, risk of resistance, and personal preference.
- Choose Botox if you prefer a well-known brand with a longer track record.
- Choose Xeomin if you want a purer formulation with a lower risk of resistance.
Always consult a board-certified dermatologist or plastic surgeon to determine the best option for your needs.
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FAQs: Xeomin vs Botox
1. Does Xeomin last longer than Botox?
Generally, both last 3-4 months, but Xeomin may last longer in patients resistant to Botox.
2. Which is safer: Xeomin or Botox?
Both are FDA-approved and considered safe. However, Xeomin’s purified formula may reduce the risk of resistance.
3. Is Xeomin cheaper than Botox?
Yes, Xeomin is usually $2-$3 per unit cheaper than Botox.
4. Can I switch from Botox to Xeomin?
Yes! Many patients switch to Xeomin if they develop Botox resistance.
Infographic: Xeomin vs Botox – Key Differences
(Infographic to be generated featuring key points on composition, cost, longevity, and side effects.)
